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AG Schwarz: Deletion of the P/Q-type calcium channel from serotonergic neurons drives male aggression in mice.
You are here:
AG Schwarz: Deletion of the P/Q-type calcium channel from serotonergic neurons drives male aggression in mice.

Deletion of the P/Q-type calcium channel from serotonergic neurons drives male aggression in mice.

In this study we could show that the P/Q-type calcium channel is mediating aggression in serotonergic neurons from the dorsal raphe nucleus via monosynaptic projections to the ventrolateral part of the ventromedial hypothalamus. Most importantly, silencing these projections reduced aggressive behavior in mice and thus may serve as a therapeutic approach for treating aggression in humans.

Please follow this link to find out more. (DOI: 10.1523/JNEUROSCI.0204-22.2022)

Contact:

Prof. Dr. Heinz Beck
Institute of Experimental Epileptology and Cognition Research
Life and Brain Center
University of Bonn Medical Center
Sigmund-Freud Str. 25
53127 Bonn

Contact:

Prof. Dr. Heinz Beck
Institute of Experimental Epileptology and Cognition Research
Life and Brain Center
University of Bonn Medical Center
Sigmund-Freud Str. 25
53127 Bonn

Contact:

Prof. Dr. Heinz Beck
Institute of Experimental Epileptology and Cognition Research
Life and Brain Center
University of Bonn Medical Center
Sigmund-Freud Str. 25
53127 Bonn