Inferring generative dynamical systems models from multimodal, multiscale, and multi-animal neuroscientific data
Speaker: Prof. Dr. Daniel Durstewitz
Affiliation: Dept. of Theoretical Neuroscience, Central Institute of Mental Health Mannheim & Interdisciplinary Center for Scientific Computing, Heidelberg University
Any biological system that is described by quantities that evolve in time and space is naturally formalized as a dynamical system. For decades dynamical systems theory played a pivotal role in theoretical and computational neuroscience, as it links biophysical and biochemical processes to neural computation. In fact, dynamical systems are computationally universal. Rather than hand-crafting computational theories of neural function based on dynamical systems, recent developments in scientific machine learning (ML) and AI suggest that we may be able to infer such dynamical-computational models directly from neurophysiological and behavioral observations. In my talk I will cover recent ML/AI architectures, training algorithms, and validation procedures toward this goal. I will discuss specifically how recent AI architectures can integrate neuroscience data from multiple modalities (like multiple single-unit recordings and behavioral choices), across diverse time scales, and across many different animals and task designs, into a joint dynamical systems model, providing steps into the direction of AI foundation models for neuroscience.
Prof. Dr. Heinz Beck Institute of Experimental Epileptology and Cognition Research Life and Brain Center University of Bonn Medical Center Sigmund-Freud Str. 25 53127 Bonn
Contact:
Prof. Dr. Heinz Beck Institute of Experimental Epileptology and Cognition Research Life and Brain Center University of Bonn Medical Center Sigmund-Freud Str. 25 53127 Bonn
Contact:
Prof. Dr. Heinz Beck Institute of Experimental Epileptology and Cognition Research Life and Brain Center University of Bonn Medical Center Sigmund-Freud Str. 25 53127 Bonn