We are interested in how initial myelination and re-myelination is organized in the central nervous system. We are using transgenic fluorescent zebrafish larvae reporter models to investigate inter- and intra-cellular communication of glial and neuronal cells involved in this process by in-vivo imaging. Recent special interests of our group are the involvement of GPRCs in myelination, the function of the fish specific myelin protein 36K as well as the general involvement of glutamate in the regulation and communication within the myelination process.