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Identifying myelination-independent roles of oligodendrocyte precursor cells for the development and function of neural circuits
You are here:
Identifying myelination-independent roles of oligodendrocyte precursor cells for the development and function of neural circuits

Date: May 26, 2023 3:00 pm

Identifying myelination-independent roles of oligodendrocyte precursor cells for the development and function of neural circuits

Speaker: Tim Czopka, Dr.

Affiliation: University of Edinburgh, Centre for Clinical Brain Sciences

Neurons are not alone in the brain. They are surrounded by a large number of glial cells which have crucial roles in shaping and maintaining structure and function of the central nervous system (CNS). Oligodendrocytes and their committed precursors represent an abundant population of CNS glia with established roles in axonal myelination. However, there are many more oligodendrocyte precursor cells (OPCs) distributed across the CNS lifelong than ever give rise to myelinating oligodendrocytes. My group investigates the mechanisms that govern oligodendrocyte differentiation in the healthy and damaged CNS, and how tissue-resident OPCs affect the CNS when they don’t make myelin. We do this using zebrafish as model organism, which allows us that carry out high-resolution imaging of intercellular interactions, along with genetic and physiological manipulations and analyses.

Host: Prof. Dr. Schoch and Prof. Dr. Dietrich

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Venue:

Epileptology, Seminar Room 266/83, Ground Floor

Contact:

Prof. Dr. Heinz Beck
Institute of Experimental Epileptology and Cognition Research
Life and Brain Center
University of Bonn Medical Center
Sigmund-Freud Str. 25
53127 Bonn

Contact:

Prof. Dr. Heinz Beck
Institute of Experimental Epileptology and Cognition Research
Life and Brain Center
University of Bonn Medical Center
Sigmund-Freud Str. 25
53127 Bonn

Contact:

Prof. Dr. Heinz Beck
Institute of Experimental Epileptology and Cognition Research
Life and Brain Center
University of Bonn Medical Center
Sigmund-Freud Str. 25
53127 Bonn